The Centre for Microbial Chemical Biology (CMCB) is a 7,000 square foot multi-user lab facility housed within the Michael G. DeGroote Institute for Infectious Disease Research (IIDR) at McMaster University. This core facility has experienced staff and over 65 specialized equipment items, enabling chemical biology research to be conducted in one central location. The CMCB is a Biosafety Level 2 facility that has the capabilities necessary for cell culture, assay development, high throughput screening, small molecule synthesis, natural product isolation, metabolomics, molecule identification for drug discovery, and basic research applications. Expert staff are on hand to maintain the equipment, offer training, and assist with the design and completion of individual research projects and experiments.
McMaster’s Biosafety Level 3 (BSL3) Lab is one of the few centres in Canada equipped to support research on the world’s most deadly infectious disease pathogens. This 1,400-square-foot lab boasts dedicated animal facilities, a state-of-the-art flow cytometry facility, and ample space for current and future projects.
Consisting of both research and clinical laboratory facilities throughout the Health Sciences Centre and the Michael G. DeGroote Centre for Learning and Discovery, this facility is accessible to a wide spectrum of investigators both inside and outside of McMaster University. It is operated in a manner that maximizes research user access and provides expertise to aid the users in experimental design and protocol development.
The Electron Microscopy Facility provides an inter-disciplinary approach to the investigation of biological, biochemical, clinical and medical areas of research. The facility offers consulting, experimental design, training, and technical services for light and electron microscopic imaging, immuno-labelling, image analysis, morphometry, and elemental analysis. It is the largest diagnostic EM Facility in Canada.
This state-of-the-art sequencing facility, located within the Farncombe institute, offers a full range of DNA sequencing technologies. Full-time staff can both sequence prepared libraries and provide full-service library construction, sequencing, and analysis. Staff also provides preliminary microbiome analysis and genome assemblies and have extensive experience with 16S bacterial profiling, genomics, metagenomics, transcriptomics, and metatranscriptomics.