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The Old with the New: The Importance of Combining Microbial Culture with DNA Sequencing for the Future of Microbiome Research

The human microbiome has been shown to be of overwhelming importance to health and disease.

A new Nature Microbiology study led by Dr. Fiona Whelan (University of Nottingham) and Dr. Michael Surette (McMaster University) demonstrates how combining the standard method of metagenomic sequencing with the microbiological culture of bacteria allows for an even deeper analysis of microbial diversity than by sequencing alone.

Such findings are key in gaining a better understanding of chronic airway diseases such as cystic fibrosis, and also applicable to gut disorders such as inflammatory bowel disease, irritable bowel syndrome, and obesity, among others.

Read the Behind the Paper article here.